weaning from ventilator and effect of blender-humidifier on outcome of it

background and objectives: the weaning procedure of mechanical ventilation in many patients is a difficult and long process and increases the time of mechanical ventilation. there are numerous ways to achieve this goal. one common way is using cpap-ventilator. considering the lower price of blender-humidifier compared to cpapof ventilator and the limited number of studies in this field, this study was aimed to compare these two procedures.methods: 102 patients in pediatric intensive care unit (picu) were allocated randomly in one group: cpap-ventilator and blender-humidifier. duration of hospital and picu stay, the number of days of mechanichal ventilation, the frequency of re-intubation, and the mortality of the patients were recorded. results: the study was conducted on 66 male and 36 female patients (64.7% and 35.3% respectively). the average age was 22.5 ± 4.5 months. the most frequent complaint of the patients at the time of visit was coughing (35%), hyperventilation and respiratory distress (21.6%). hospital stay was 23±14 and 20±12days in humidifier and cpap groups respectively (p=0/52).picu stay was 15± 11and 20±11 days in humidifier and cpap groups respectively (p=0/18).re- intubation rate was 16/2% and 33/5% in humidifier and cpap groups respectively (p=0/15).mortality rate 8/4% and 21.5% in humidifier and cpap groups respectively (p=0/06). conclusion: although there was no statistically significant difference between two groups, considering the differences in mortality rate, the need for re-intubation, rate of hospital and picu stay, and at the same time, with easy availability and low prices, using blender- humidifier is recommended.